IFN-a/b Receptor Signaling Promotes Regulatory T Cell Development and Function under Stress Conditions
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چکیده
منابع مشابه
IFN-α/β receptor signaling promotes regulatory T cell development and function under stress conditions.
Type I IFNs are a family of cytokines with antiviral and immunomodulatory properties. Although the antiviral effects of IFNs are well characterized, their immunomodulatory properties are less clear. To specifically address the effects of type I IFNs on T regulatory cells (Tregs), we studied mixed bone marrow chimeras between wild-type and IFN-α/β receptor (IFNAR) knockout (KO) mice, and heteroz...
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